Development of Prescribed Safer Supply in Canada

"The extremely potent and toxic nature of ISOs [Illicit/Synthetic Opioids] has rendered them the primary cause of overdose fatalities while consequently presenting major challenges for the menu of available interventions. Many existing interventions have mostly aimed at either manipulating the drug use environment to be safer (e.g., supervised consumption) or reactively treating underlying drug use disorders (OAT) or overdoses (naloxone).

Overdose Prevention Centers, Crime, and Public Order

"Results  No significant changes were detected in violent crimes or property crimes recorded by police, 911 calls for crime or medical incidents, or 311 calls regarding drug use or unsanitary conditions observed in the vicinity of the OPCs. There was a significant decline in low-level drug enforcement, as reflected by a reduction in arrests for drug possession near the OPCs of 82.7% (95% CI, −89.9% to −70.4%) and a reduction in their broader neighborhoods of 74.5% (95% CI, −87.0% to −50.0%).

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