"Prison population rates vary considerably between different regions of the world, and between different parts of the same continent. For example:

"• in Africa the median rate for western African countries is 53 whereas for southern African countries it is 244;

"• in the Americas the median rate for south American countries is 233 whereas for central American countries it is 316;

"• in Asia the median rate for countries in southern Asia (mainly the Indian subcontinent) is 88 whereas for central Asian countries it is 160.5;

(Failure of Law Enforcement Interventions) "Based on the available English language scientific evidence, the results of this systematic review suggest that an increase in drug law enforcement interventions to disrupt drug markets is unlikely to reduce drug market violence.

"Mitragyna speciosa Korth (of the Rubiaceae family) is a large tree found in tropical and sub-tropical regions of South-East Asia. In Thailand, the tree known as ‘Kratom’ is found throughout the country but predominantly in the southern region, although the growing and harvesting is prohibited.

"Over the past 15 years, six RCTs [Randomized Controlled Trials] have been conducted involving more than 1,500 patients, and they provide strong evidence, both individually and collectively, in support of the efficacy of treatment with fully supervised self-administered injectable heroin, when compared with oral MMT, for long-term refractory heroin-dependent individuals.