Cannabis and Driving: "Epidemiological studies have been inconclusive regarding whether cannabis use causes an increased risk of motor vehicle accidents; in contrast, unanimity exists that alcohol use increases crash risk.30 In tests using driving simulation, neurocognitive impairment varies in a dose-related fashion, and symptoms are more pronounced with highly automatic driving functions than with more complex tasks that require conscious control.31 Cannabis smokers tend to over-estimate their impairment and compensate effectively while driving by utilizin
"As noted in the illicit drug use section, an estimated 24.0 million Americans aged 12 or older in 2016 were current users of marijuana (Figure 15). This number of past month marijuana users corresponds to 8.9 percent of the population aged 12 or older (Figure 17). The percentage of people aged 12 or older who were current marijuana users in 2016 was higher than the percentages from 2002 to 2015.
Lung Cancer Risk from Cannabis Use: "Despite these findings, the small number of observational studies fail to demonstrate a clear association between marijuana smoking and diagnoses of lung cancer. Therefore, we must conclude that no convincing evidence exists for an association between marijuana smoking and lung cancer based on existing data.
Marinol Withdrawal: "An abstinence syndrome has been reported after the abrupt discontinuation of dronabinol [Marinol®] in volunteers receiving dosages of 210 mg/day for 12 to 16 consecutive days. Within 12 hours after discontinuation, these volunteers manifested symptoms such as irritability, insomnia, and restlessness. By approximately 24 hours post-dronabinol discontinuation, withdrawal symptoms intensified to include 'hot flashes', sweating, rhinorrhea, loose stools, hiccoughs and anorexia.
Cannabinoid Withdrawal: "The withdrawal syndrome associated with dronabinol, the API [Active Pharmaceutical Ingredient] in Marinol®, produces symptoms in humans such as restlessness, irritability, mild agitation, anxiety, anger, insomnia, sleep EEG disturbances, nausea, decreased appetite, and decreased weight.
Marijuana Use Among 50-Year-Olds in the US, 2012: "Among 50-year-old high school graduates in 2012, we estimate that about three quarters (74%) have tried marijuana, and that about two thirds (64%) have tried an illicit drug other than marijuana. (These estimates are adjusted to correct for panel attrition, as described in chapter 4 of Volume II.)
Prevalence of Marijuana Use in the US, by State, 2009-2010: "In 2009-2010, past month marijuana use was reported by 6.8 percent of the U.S. population aged 12 years or older, an increase from 6.4 percent in 2008-2009 (Table C.3). Nine States that were in the top fifth for past month illicit drug use among persons aged 12 or older also were ranked in the top fifth for past month marijuana use: Alaska, Colorado, District of Columbia, Maine, Massachusetts, New Hampshire, Oregon, Rhode Island, and Vermont (Figures 2.1 and 2.9).
Harms of Cannabis Versus Harms of Prohibition: "Based on the research to date, the harms associated with the actual use of cannabis likely pale in comparison with the widely observed harms attributable to cannabis prohibition. As such, policymakers should integrate the scientific research conducted on the likely impacts of current prohibitive approaches to cannabis use into the process of optimising cannabis policy."
"‘Spice’ and other ‘herbal’ products are often referred to as ‘legal highs’ or ‘herbal highs’, in reference to their legal status and purported natural herbal make-up (McLachlan, 2009; Lindigkeit et al., 2009; Zimmermann et al., 2009). However, albeit not controlled, it appears that most of the ingredients listed on the packaging are actually not present in the ‘Spice’ products and it is seems likely that the psychoactive effects reported are most probably due to added synthetic cannabinoids, which are not shown on the label.
Cannabis and Driving Impairment: "Participants receiving active marijuana decreased their speed more so than those receiving the placebo cigarette during a distracted section of the drive, An overall effect of marijuana was seen for the mean speed during the distracted driving (PASAT [Paced Auditory Serial-Addition Test] section), While no other changes in driving performance were found, marijuana appeared to hinder practice effects on the PASAT task, suggesting individuals may not be able to adequately use information and experience previously acquired while under t