Neonatal Abstinence Syndrome

"Neonatal abstinence syndrome (NAS) is a drug withdrawal syndrome in newborns following birth. The syndrome most commonly occurs in the context of antepartum opiate use, although other drugs have also been implicated.2-5 In addition to NAS, illicit drug use (specifically opioid dependence) during pregnancy is associated with a significantly increased risk of adverse neonatal outcomes such as low birthweight (


Patrick, Stephen W.; Schumacher, Robert E.; Benneyworth, Brian D.; Krans, Elizabeth E.; McAllister, Jennifer M.; and Davis, Matthew M., "Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009," Journal of the American Medical Association (Chicago, IL: American Medical Association, April 30, 2012), p. E1.