(Effects of Amphetamine and Methamphetamine Use) "A paranoid psychosis may result from long-term use; rarely, the psychosis is precipitated by a single high dose or by repeated moderate doses. Typical features include delusions of persecution, ideas of reference (notions that everyday occurrences have special meaning or significance personally meant for or directed to the patient), and feelings of omnipotence. Some users experience a prolonged depression, during which suicide is possible. Recovery from even prolonged amphetamine psychosis is usual but is slow.
(Treatment for Amphetamine Overdose) "When significant oral toxicity is recent (eg, < 1 to 2 h), activated charcoal may be given to limit absorption, although this intervention has not been shown to reduce morbidity or mortality. Urinary acidification hastens amphetamine excretion, but it may worsen myoglobin precipitation in the renal tubules and thus is not recommended.
(Methamphetamine Overdose) "Toxicity or overdose: Tachycardia, arrhythmias, chest pain, hypertension, dizziness, nausea, vomiting, and diarrhea can occur. CNS effects include acute delirium and toxic psychosis. Overdose can also cause stroke (usually hemorrhagic), seizures, muscle rigidity, and hyperthermia (> 40° C); all of these effects may precipitate rhabdomyolysis, which can lead to renal failure."
(Prenatal Methamphetamine Exposure) "Although research on the medical and developmental effects of prenatal methamphetamine exposure is still in its early stages, our experience with almost 20 years of research on the chemically related drug, cocaine, has not identified a recognizable condition, syndrome or disorder that should be termed 'crack baby' nor found the degree of harm reported in the media and then used to justify numerous punitive legislative proposals.
(Lab Fires and Explosions) "Further contributing to the threat posed by the trafficking and abuse of methamphetamine, some chemicals used to produce methamphetamine are flammable, and improper storage, use, or disposal of such chemicals often leads to clandestine laboratory fires and explosions. National Clandestine Laboratory Seizure System (NCLSS) 2003 data show that there were 529 reported methamphetamine laboratory fires or explosions nationwide, a slight decrease from 654 reported fires or explosions in 2002."
(Growth of Clandestine Labs) "The incidence of clandestine drug laboratories has grown dramatically in the past 10 years. For example, in Fiscal Year 1992, the DEA's National Clandestine Laboratory Cleanup Program funded approximately 400 removal actions and by fiscal year 2001, the DEA Program funded more than 6,400 removal actions."
Of the 224,982 sale/manufacture arrests in 2018, 72,788 were for heroin, cocaine, and derivatives; 54,591 were for marijuana; 29,777 were for synthetic or manufactured drugs; and 66,171 were for other dangerous nonnarcotic drugs.
"Increases in methamphetamine indicators reported in 2012 continued into 2013. These increases reversed a mostly declining trend since 2007. All CEWG area representatives reported increasing, stable, or mixed indicators in 2013, compared with 2012. Twelve of 19 CEWG area representatives reported increasing methamphetamine indicators in the 2013 reporting period; these were Atlanta, Cincinnati, Denver/Colorado, Detroit, Los Angeles, Minneapolis/St. Paul, St. Louis, San Diego, San Francisco, Seattle, South Florida/Miami-Dade and Broward Counties, and Texas.